Overstrain, or toxins in the blood, may bring about this stiffening of the arteries too soon, and then, we say that the person is "old before his time.
He said we didn't have to stay at Detrick producing the toxins and aerosols that will destroy millions of lives.
They want me to produce even deadlier toxins than those I gave them," Dell said viciously.
Many diseases, if severe, not only leave the body in a weakened condition, but may, through the toxins which the germs deposit, cause untold harm if the patient leaves his bed or resumes his usual activities too soon.
These consist of minute organisms that find their way into the body and, by living upon the tissues and fluids and by depositingtoxins (poisons) in them, cause different forms of disease.
They attack certain glands in the walls of the small intestine, where they produce toxins that pass with the germs to all parts of the body.
This resistance of unicellular beings to many microbes and microbian toxins is due not only to the intense digestive power of the cell but also to the extreme sensitiveness which rules over the choice of food.
In those cases, when microbes and toxins are digested by the same cells, the latter manufacture antibodies against both.
The dissolution of this fatty substance produces toxins which pass into the urine.
He ascertained that the vaccination of animals bytoxins conferred, after a time, antitoxic powers to the blood and humors which contained leucocytes.
As to antitoxic immunity, it is very probably due to the intracellular digestion of toxins by the different macrophages.
He reviewed this flora and pointed out the harmful effect of the microbes, especially those of the large intestine the toxins of which effect a chronic poisoning of the cells of our organism and thus provoke their gradual weakening.
All those facts confirmed anterior results which Metchnikoff had obtained, and indicated the route to be followed in his struggle against those toxins which gradually poison the organism and induce premature senility.
However, certain observations on toxins and antitoxins pleaded in favour of this thesis.
On the other hand, a microbian vaccination is preventive against microbes only but not against toxins and the blood does not become antitoxic.
As I attributed my condition to poisoning by the toxins of intestinal microbes, I resolved to give up raw food and to purge myself now and then with Carabana water.
As toxins are absorbed and digested chiefly by macrophages, it is probable that it is the latter also which manufacture specific antitoxins, or the final product of the digestion of corresponding toxins.
He demonstrated that the principal cause is the chronic poisoning of the cells by toxins manufactured by microbes in the intestine.
For it is they which absorb and digest toxins as well as soluble poisons.
It seemed that all other therapeutic factors must give way to definitely accurate doses of antitoxic principles, directly opposed to the toxins of disease and {70} capable of conquering it.
The exact nature of the physiological effects which are produced by these mineral toxins is not clearly understood; indeed, it is probably different in the case of different metals.
Hence, it is probably inaccurate to discuss the toxins as a distinct group of substances.
Doses of organisms or their toxins can be injected on one or several occasions, and provided that the lethal dose be not reached, in most cases an increased power of resistance is produced.
The physiological effect produced may be due to the toxins or poisonous matters that are given off by the parasite while it is living in the host's body.
The nervous system seems to be affected by the parasite, either directly or by the action of the toxins it produces.
Before the year was gone, the imps of morbid toxins came into their own and she resorted to wines, later to alcohol in stronger forms--and alcohol usually makes short work of the fineness God gives woman.
The heart is sometimes attacked by the toxins of the disease, and permanent damage to the organ, in the form of valvular trouble, may result.
If this has happened, the bacteria multiply rapidly, and the toxins that are formed are taken up by the lymphatics and carried away from the tissues as fast as possible.
If subjected to cooking at a temperature of at least the boiling point, comparative safety is secured; but the toxins accompanying the disease germs in the infected food are not as a rule rendered harmless.
It is due to the absorption into the systems of these children of the toxins formed during the putrefying of milk in the stomachs and bowels of the little sufferers.
On the other hand, the administration of one large normal saline enema by supplying the tissues with fluids, and probably thereby diluting the toxins circulating in the system, gives considerable relief.
The definite nature of the symptoms in the majority of the forms of acute insanity leave little reason to doubt that they result from an invasion of the system by toxins of various kinds.
The toxins act either directly on the brain cells producing a state of irritability incompatible with sleep, or indirectly, producing physical symptoms which of themselves alone are capable of preventing the condition of sleep.
Until the pathology of these affections is better understood we are not in a position to determine the nature of the toxins which appear to be the cause of these diseases and of their accompanying nervous symptoms.
There are substances in the fluid part of the blood which are called antitoxins, because they neutralise the toxins produced by the bacteria.
Their presence constitutes a means of defence against the harmful effects the toxins would otherwise produce.
They are probably not to be classed with the so-called true toxins generated by the diphtheria and tetanus bacilli, since there is no evidence that they give rise to antibodies when injected into susceptible animals.
Clinical symptoms, and the presence of bacteria in the inflamed tissue indicate that bacteria and their toxins play an important part in the development of articular rheumatism.
It is commonly caused by taking into the body with the feed and water certain organisms and toxins that are capable of producing an inflammation of the brain.
The Schmidt theory is that certain toxins are formed in the udder, owing to the over activity of the cells of the glandular tissue.
The specific germ remains at the point of infection, and produces toxinsthat cause tetanic contractions of the muscles.
The infectious organism or toxins are taken up by the absorbing vessels of the intestines.
But insanity is a physical disease, implying changes or toxins in the brain cells.
The toxins and poisons in the nervous system at such times operate to prevent the formation of new habits and the breaking of old ones.
The repeated stimulation of certain muscles produces fatigue toxins which impair the efficiency of response and make further stimulation painful.
Like the extracellular toxins they may be of remarkable potency; for example, fever is produced in the human subject by the injection into the blood of an extremely minute quantity of dead typhoid bacilli.
This, for example, is the case with the anthrax bacillus; although the effect of this organism in the living body indicates the production of toxins which diffuse for a distance around the bacteria.
In such diseases the bacteria, when introduced into the subcutaneous tissue, rapidly gain entrance to the blood stream and multiply freely in it, and by means of theirtoxins cause symptoms of general poisoning.
Though the causal relationship of a bacterium to a disease may be completely established by the methods given, another very important part of bacteriology is concerned with the poisons or toxins formed by bacteria.
The action of toxinson various glands, producing diminished or increased functional activity, has a close analogy to that of certain drugs.
Many of them, probably also of proteid nature, are much more resistant to heat; thus the intracellular toxins of the tubercle bacillus retain certain of their effects even after exposure to 100° C.
The study of the nature of toxins requires, of course, the various methods of organic chemistry.
Such toxins being set free in the culture medium are often known as extracellular.
In other instances the toxins are retained to a large extent within the bacteria, and in this case the dead bacteria are injected as a suspension in fluid.
These toxins may become free in the culture fluid, and the living bacteria may then be got rid of by filtering the fluid through a filter of unglazed porcelain, whose pores are sufficiently small to retain them.
Regarding the chemical nature of toxins less is known than regarding their physiological action.
Immunity against toxins also became a subject of investigation, and the result was the discovery of the antitoxic action of the serum of animals immunized against tetanus toxin by E.
Toxins are thus formed in the body which may pass to the human being eating the flesh, and in this way poisons called ptomaines are produced, resulting in so-called toxic poisoning.
The action of the germ is followed by the formation of poisons or toxins which are distributed by the blood through the body, causing the fever and what are known as "general symptoms.
It is also true that if the disease germs could be destroyed within the body the patient would recover immediately, provided the toxins had not been already distributed through the system.
Instead of the introduction of toxins into the body by the agency of bacteria, it is quite possible for chemical poisons, not formed originally by bacteria, to be set free in the body.
If the germs have secured a foothold in the upper throat, then the well-known membrane is formed and the toxins produced spread through the blood and cause headache and fever, even before any experience of sore throat is felt.
He was perfectly convinced that, since the force that underlay the production of Toxins could accomplish so much, it could surely accomplish everything.
Roughly speaking, I think his general position was that as Toxins are a secretion of microbes (I am certain of that phrase, anyhow), so thought and spiritual experiences and so forth are a secretion of the brain.
The immunising substances or anti-toxins which are doubtless produced in the smoker's blood may protect the germ-plasm which he bears as well as his own body.
A Keats, a Spinoza, or a Schubert must go under if his factors of survival-value do not enable him to resist those of the tubercle bacillus, its toxins or poisons.
In the case of the parasitic microbe it is an evil character, the power to produce toxins or poisons.
On account of the fever with which the animal suffers, the flesh contains toxins that may render it poisonous to the consumer.
In some cases the brain appears to become disordered, probably from the pain and weakness and from the absorption of toxins generated in the digestive canal.
Septicemia was formerly applied to designate the condition in which the organisms were localized, but in which their toxins were diffused in the blood.
The Nature of the Antagonism betweenToxins and Antitoxins,” Proceedings of the Royal Society of London, vol.
Roux and Behring, with reference to the toxins of diphtheria and tetanus, and I could not allow the chance to escape.
In a very important memoir on the reconstitution of the toxins from a mixture of toxin + antitoxin, J.
Cherry and Martin on antagonism between toxins and antitoxins, 253.
These highly complex substances are composed of mixtures of poisons, some of which are in all respects analogous to the vegetable alkaloids, while others are closely related to the microbic toxins and snake-venoms.
Alcohol exerts a similarly deteriorating influence on the antitoxin-forming organs (especially on the testicles, ovaries and their appendages), to that already described as exerted by the toxins of the contagions and infections.
And thus the high hopes and claims attached to the sero-therapy inocculation process, the injection into the blood of anti-toxins prepared with the serum of animals, have positively vanished.
When the toxins are in the ascendency the patient suffers more and more acutely, and may succumb before there has been time for the formation in his own body of the antitoxins.
First, there is an ordinary inflammatory irritation, and secondly, there is a specific change set up by the toxins of the bacillus.
However the details of the modus operandi of the formation of toxins are finally settled, we know that there comes a time when the disease symptoms vanish, the disease declines, and the patient recovers.
To be of value, antitoxins must be used as early as possible, before tissue change has occurred and before the toxins have, so to speak, got the upper hand.
The antitoxins are now ready for injection into the patient who has contracted diphtheria, and in whose blood toxins are in the ascendency and under which the individual may succumb.
The progress of disease is therefore a struggle between the toxins and the antitoxins: when the toxins are in the ascendency we get an increase of the disease; when the antitoxins are in the ascendency we get a diminution of disease.
The toxinsact on the blood-vessels, and nerves, and muscle fibres of the heart, and many of the more highly specialised cells of the body.
Lastly, we may turn to consider the action of the toxinson the individual in whose body-fluids they are formed.
In diphtheria, as we have seen, the toxins turned out to be soluble bodies allied to the proteids, albumoses, and an organic acid.
The above list will hopefully give you a few useful examples demonstrating the appropriate usage of "toxins" in a variety of sentences. We hope that you will now be able to make sentences using this word.
